Jianli Lu , Lianming Zhang

Traditional Chinese Medicine Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, China
Author    Correspondence author
Biological Evidence, 2024, Vol. 14, No. 2   doi: 10.5376/be.2024.14.0008
Received: 01 Feb., 2024    Accepted: 09 Mar., 2024    Published: 21 Mar., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Lu J.L., and Zhang L.M., 2024, Exploring the genome of Rehmannia glutinosa: understanding its genetic code and medicinal potential, Bioscience Evidence, 14(2): 56-68 (doi: 10.5376/be.2024.14.0008)

The main objective of this study is to explore the genome of Rehmannia glutinosa to elucidate its genetic code and understand the underlying mechanisms responsible for its medicinal properties. By integrating genomic data with traditional knowledge, this study aims to identify key bioactive compounds and their biosynthetic pathways, as well as the genetic variability within natural populations, providing insights into breeding strategies and biotechnological applications. Genomic research on Rehmannia glutinosa has revealed a complex genetic landscape with significant variability among natural populations. Key bioactive compounds, including iridoids, phenylethanoids, and polysaccharides, have been identified along with their respective biosynthetic pathways. Advances in genetic engineering and tissue culture techniques have facilitated the enhancement of medicinal traits and the large-scale production of high-quality plant material. Additionally, the integration of traditional knowledge with genomic data has led to the development of more effective and standardized herbal formulations. The findings from genomic research on Rehmannia glutinosa provide a comprehensive understanding of its genetic code and medicinal potential. These insights pave the way for the development of improved therapeutic agents and sustainable cultivation practices. Future research should focus on overcoming current genomic limitations, exploring genetic diversity, and leveraging synthetic biology for the scalable production of bioactive compounds. The interdisciplinary approach combining traditional wisdom with modern science holds great promise for unlocking the full medicinal potential of Rehmannia glutinosa.

Rehmannia glutinosa; Traditional Chinese medicine; Genomic research; Bioactive compounds; Medicinal properties; Genetic diversity; Breeding strategies; Genetic engineering