Guangman Xu , Jiayi Wu

Traditional Chinese Medicine Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
Biological Evidence, 2026, Vol. 16, No. 4   
Received: 09 Jul., 2026    Accepted: 10 Aug., 2026    Published: 20 Aug., 2026

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Dendrobium officinale Kimura et Migo is a valuable medicinal orchid, and its medicinal properties and industrial applications mainly depend on stem yield and the accumulation of bioactive compounds, including polysaccharides, flavonoids, and alkaloids. However, with the rapid expansion of artificial cultivation, several challenges have emerged, such as unstable quality, poor environmental adaptability, and incomplete quality evaluation systems. Environmental conditions play an important role in regulating the growth and quality formation of D. officinale, affecting plant morphology, photosynthetic processes, biomass accumulation, and the biosynthesis of active compounds. This review summarizes the main growth and quality evaluation indicators of D. officinale and focuses on the effects of environmental factors, including light conditions, temperature and humidity, cultivation substrates, and water and fertilizer management, on plant growth and medicinal quality formation. In addition, typical cases involving local germplasm utilization, different cultivation systems, regional variation, and quality evaluation are discussed to clarify the role of environmental regulation in improving cultivar adaptation, enhancing active compound accumulation, and maintaining stable medicinal quality. Based on these findings, future development directions are proposed, including standardized environmental control, multidimensional quality evaluation systems, and intelligent cultivation technologies. This review summarizes the key environmental factors affecting high-quality production of D. officinale and provides theoretical support and practical references for its standardized, precise, and sustainable cultivation.

Dendrobium officinale; Environmental regulation; Quality formation; Medicinal compounds; Precision cultivation