Xiaoyan Chen

Traditional Chinese Medicine Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, China
Author    Correspondence author
Genomics and Applied Biology, 2025, Vol. 16, No. 1   
Received: 03 Dec., 2024    Accepted: 11 Jan., 2025    Published: 27 Jan., 2025

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study aims to explore the genomic foundations of Achyranthes bidentata's medicinal potential and evolutionary traits. By synthesizing current research, we seek to understand the genetic markers, evolutionary adaptations, and pharmacological properties that contribute to its therapeutic efficacy and evolutionary success. Key discoveries include the identification of biosynthetic and transport genes associated with medicinal components such as oleanolic acid and ecdysterone. Adaptive genetic variations driven by environmental factors, particularly temperature and precipitation, have been identified, highlighting the species' ecological adaptability. Comparative chloroplast genome analysis has revealed a highly conserved structure among Achyranthes species, supporting their monophyletic origin and close phylogenetic relationships. Additionally, novel polysaccharides and fructooligosaccharides from A. bidentata have demonstrated significant antioxidant and osteoprotective activities, further underscoring its medicinal potential. The genomic insights into Achyranthes bidentata provide a deeper understanding of its medicinal properties and evolutionary adaptations. These findings have significant implications for the development of new pharmacological agents and the conservation of this valuable medicinal plant. Future research should focus on elucidating the structure-activity relationships of its bioactive compounds and the long-term effects of its therapeutic use.

Achyranthes bidentata; Genomic studies; Medicinal plants; Evolutionary traits; Pharmacogenomics