Baohua Dong , Linfei Jin

Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
Genomics and Applied Biology, 2025, Vol. 16, No. 2   
Received: 03 Feb., 2025    Accepted: 10 Mar., 2025    Published: 27 Mar., 2025

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The study summarizes the current genomic results on how Channa fish adapt to hypoxia. We performed high-quality genome assembly and transcriptome analysis on Channa asiatica. The results showed that it has more gene families related to oxygen binding and transport. When it is exposed to air, many pathways related to oxidative stress are activated. This shows that it has the genetic ability to adapt to hypoxia and also reveals some of the molecular mechanisms. We also studied gene expression in the liver of Channa striatus under long-term hypoxia. We found that many genes involved in transcription, translation, signal transduction, electron transport and immune response were activated. Several transcripts related to hypoxia tolerance were also identified, such as heat shock protein 90 and fatty acid binding protein, and we also obtained their complete sequences. These research results provide important genomic and transcriptome resources, which will help us to better understand how Channa fish adapt to low oxygen environments. At the same time, it also lays a foundation for future research on hypoxia tolerance breeding and ecological adaptation.

Channa genus; Hypoxia tolerance; Genomics; Transcriptome; Molecular mechanism