Single Course of Antibiotics Early in Life May Increase Type 1 Diabetes Risk
Published:29 Jul.2018 Source:GEN
Research by scientists in the U.S. and U.K. has demonstrated how a single course of antibiotics given early in life can significantly increase the risk of developing type 1 diabetes (T1D), at least in a mouse model.
The studies, headed by Martin Blaser, M.D., director of the Human Microbiome Program at New York University (NYU) School of Medicine, found that giving very young diabetes-predisposed mouse pups a single, 5-day therapeutic course of antibiotics resulted in “deep and persistent” effects on the intestinal microbiome, which accelerated and enhanced T1D development.