Ground-breaking Study Reveals Dynamics of DNA Replication ‘Licensing’
Published:26 Jan.2022    Source:University of North Carolina Health Care

A new study from scientists at the UNC School of Medicine has illuminated an important process that occurs during cell division and is a likely source of DNA damage under some circumstances, including cancer.

The scientists, who reported their findings in Nucleic Acids Research, devised a sophisticated experimental platform for studying the process called "origin licensing." Cells use this process to regulate, or "license" the replication of their genomes during cell division.