Chumki Bhattacharjee¹ , Doddananjappa Theertha Prasad² , Nagenahalli Huchappa Manjunat³ , Debarshi Sanyal⁴ , Sajad Majeed Zargar⁵

1 Biochemistry Department, Garden City College, 16th KM, Old Madras Road, Bangaluru, 560 049, India
2 Department of Biotechnology, University of Agricultural Sciences, GKVK, Bangaluru, 560065, India
3 Biochemistry Division, Department of Chemistry, Central College Campus, Bangalore University, Bangaluru, 560001, India
4 Lilac Insight Pvt Ltd., Ambeience court, Vashi, Navi Mumbai, 400705, India
5 School of Biotechnology, SKUAST-J, Chatha, Jammu-180009, India
Author    Correspondence author
Genomics and Applied Biology, 2012, Vol. 3, No. 2   doi: 10.5376/gab.2012.03.0002
Received: 09 Jul., 2012    Accepted: 31 Jul., 2012    Published: 10 Aug., 2012

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Chumki et al., 2012, Exploring plant proteinase inhibitors, Genomics and Applied Biology, 2012, Vol.3 No.2 8-21 (doi: 10.3969/gab.2012.03.0002)

Proteinase Inhibitors (PIs) are small, natural antagonists of proteinases and present in all life forms. PIs are widely present in plants and often found in storage organs. They are known to be inducible in plants by injuries, such as insect damage. PIs have enormous diversity of function through regulation of target proteinases. Various plant sources have been explored for isolating PIs and broad-spectrum of biological activities have been elucidated. A range of strategies have been attempted to improve effectiveness of proteinaseinhibitors as antimetabolites towards insects, bacteria and fungi. Much emphasis is yet to be given to address the health benefits of the PIs and implementing it in the most available forms throughout.

Serine proteinase inhibitor; Trypsin inhibitor; Insect pest; Cloning