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Comprehensive Genomic Analysis of Atractylodes macrocephala: Unveiling Its Medicinal Functions and Genetic Secrets  

Xichen Wang , Huixian Li , Chuchu Liu
Institute of Life Sciences, Jiyang Colloge of Zhejiang A&F University, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
Bioscience Methods, 2024, Vol. 15, No. 5   doi: 10.5376/bm.2024.15.0025
Received: 13 Aug., 2024    Accepted: 25 Sep., 2024    Published: 18 Oct., 2024
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Wang X.C., Li H.X., and Liu C.C., 2024, Comprehensive genomic analysis of Atractylodes macrocephala: unveiling its medicinal functions and genetic secrets, Bioscience Methods, 15(5): 244-254 (doi: 10.5376/bm.2024.15.0025)

Abstract

Atractylodes macrocephala is a key herb in traditional medicine with diverse medicinal properties. This study provides an overview of its botanical, phytochemical, pharmacological, and genomic aspects, highlighting its potential in modern medicine and agriculture. The study covers the morphological characteristics, geographic distribution, and cultivation techniques of A. macrocephala. It details the phytochemical composition, methods of analysis, and biological activities. Traditional medicinal uses and pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, and antiviral properties are discussed. Genomic analysis includes genome sequencing, functional gene annotation, and comparative genomics. The genetic basis of medicinal properties, including key genes and pathways, phytochemical biosynthesis, and pharmacological activities, is examined. Biotechnological applications like genetic engineering, breeding, conservation, and synthetic biology are also studyed. This study consolidates knowledge on A. macrocephala, emphasizing its traditional and modern applications. Future research should address knowledge gaps, leverage emerging technologies, and integrate genomic data with traditional knowledge to enhance its medicinal and agricultural use.

Keywords
Atractylodes macrocephala; Traditional medicine; Phytochemicals; Genomic analysis; Biotechnological applications
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