Feature Review
Comprehensive Genomic Analysis of Atractylodes macrocephala: Unveiling Its Medicinal Functions and Genetic Secrets
Author Correspondence author
Bioscience Methods, 2024, Vol. 15, No. 5 doi: 10.5376/bm.2024.15.0025
Received: 13 Aug., 2024 Accepted: 25 Sep., 2024 Published: 18 Oct., 2024
Wang X.C., Li H.X., and Liu C.C., 2024, Comprehensive genomic analysis of Atractylodes macrocephala: unveiling its medicinal functions and genetic secrets, Bioscience Methods, 15(5): 244-254 (doi: 10.5376/bm.2024.15.0025)
Atractylodes macrocephala is a key herb in traditional medicine with diverse medicinal properties. This study provides an overview of its botanical, phytochemical, pharmacological, and genomic aspects, highlighting its potential in modern medicine and agriculture. The study covers the morphological characteristics, geographic distribution, and cultivation techniques of A. macrocephala. It details the phytochemical composition, methods of analysis, and biological activities. Traditional medicinal uses and pharmacological activities such as antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, and antiviral properties are discussed. Genomic analysis includes genome sequencing, functional gene annotation, and comparative genomics. The genetic basis of medicinal properties, including key genes and pathways, phytochemical biosynthesis, and pharmacological activities, is examined. Biotechnological applications like genetic engineering, breeding, conservation, and synthetic biology are also studyed. This study consolidates knowledge on A. macrocephala, emphasizing its traditional and modern applications. Future research should address knowledge gaps, leverage emerging technologies, and integrate genomic data with traditional knowledge to enhance its medicinal and agricultural use.
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