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The Molecular Mechanisms and Regulatory Network of the Accumulation of Leonurus japonicus Alkaloids  

Jianli Zhong
Hainan Institute of Biotechnology, Haikou, 570206, Hainan, China
Author    Correspondence author
Computational Molecular Biology, 2025, Vol. 15, No. 2   
Received: 27 Jan., 2025    Accepted: 08 Mar., 2025    Published: 29 Mar., 2025
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

This study investigates the molecular mechanisms and regulatory networks that control the accumulation of alkaloids in Leonurus japonicus, a medicinal plant widely used in gynecological treatments, recognized for its antioxidant, anti-inflammatory, and anti-melanogenesis properties. Alkaloids such as Leonurine are key active compounds in the plant, playing a crucial role in its medicinal properties. This research explores the biosynthetic pathways of these alkaloids and identifies environmental factors, such as pH and external stresses, that influence their production. By integrating genomic, transcriptomic, and metabolomic analyses, the study aims to deepen the understanding of how these alkaloids contribute to the plant's medicinal characteristics, helping to optimize cultivation and medicinal application strategies, ensuring the sustainability and effectiveness of Leonurus japonicus as a medicinal resource.

Keywords
Leonurus japonicus; Alkaloids; Leonurine; Biosynthesis; Medicinal properties
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