Danyan Ding

Institute of Life Sciences, Zhejiang A&F University, Zhuji, 311800, China
Author    Correspondence author
Bioscience Methods, 2024, Vol. 15, No. 1   doi: 10.5376/bm.2024.15.0002
Received: 17 Dec., 2023    Accepted: 27 Jan., 2024    Published: 11 Feb., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Ding D.Y., 2024, The role and challenges of genome-wide association studies in revealing crop genetic diversity, Bioscience Method, 14(1): 8-19 (doi: 10.5376/bm.2024.15.0002)

Genome-wide association studies (GWAS) have shown remarkable achievements in the study of crop genetic diversity, providing a powerful tool for crop improvement by identifying genetic markers and genes related to key agronomic traits. However, GWAS faces challenges such as the complexity of population structure, the difficulty of detecting rare variants and small-effect variants, and the complexity of result interpretation. This study aims to combine new technologies such as CRISPR/Cas9 gene editing and GWAS results. Integrating multi-omics data (such as transcriptomics, proteomics) and GWAS will improve the ability to analyze traits, deeply understand the complex mechanisms of trait formation, and accelerate crop production. Character improvement. This study also emphasizes the importance of protecting and rationally utilizing crop genetic resources, hoping that GWAS will exert greater potential in crop genetic research and improvement in the future, with a view to contributing to the sustainable development of agriculture.

Genome-wide association studies (GWAS); Crop improvement; Genetic diversity; Gene editing; Multi-omics integration