Jian Song , Rongguo Li , Yue Zhao , Si Liu , Yujuan Kang , Dongwei Zhang

The Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, China
Author    Correspondence author
Computational Molecular Biology, 2015, Vol. 5, No. 2   doi: 10.5376/cmb.2015.05.0002
Received: 01 Jan., 2015    Accepted: 25 Jan., 2015    Published: 28 Jan., 2015

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Long non-coding RNA (lncRNA) is a group of length more than 200 nucleotides, the lack of complete open reading frame and no protein-coding function RNAs, which play an important role during the development of breast cancer and other malignant tumors. With the evolution of molecular biology, gene therapy of tumor has been the most intensively studied recent years. Compared with microRNA, the functional roles of lncRNAs are still being elucidated. Therefore, it is hopeful to provide new thoughts for diagnosis and treatment of tumor gene level by deepening the study of lncRNAs.

lncRNAs; Mechanisms; Breast cancer; Gene